NAMPT inhibitor-linker 2

SKU: orb1987908

Description

NAMPT inhibitor-linker 2 is a conjugate designed for constructing antibody-drug conjugates (ADCs). When conjugated to an anti-c-Kit antibody as ADC-4, it exhibits potent in vitro cytotoxicity against c-Kit-positive cancer cell lines such as GIST-T1 and NCI-H526. This makes it a valuable tool for researching targeted cancer therapies in preclinical models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2241014-82-2
• MW: 624.66
• Formula: C₃₄H₃₃FN₆O₅
• SMILES: C(NC1=CC(F)=C(CNC(=O)C2=CC=C(C=C2)N3CCN(C(CCN4C(=O)C=CC4=O)=O)CC3)C=C1)(=O)[C@@H]5[C@H](C5)C=6C=CC=NC6
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137628673