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Nampt-IN-16

SKU: orb3134957

Description

Nampt-IN-16 (Compound 9a) is an orally active NAMPT inhibitor with an IC50 of 0.15 μM. It reduces intracellular NAD+ and ATP levels. Nampt-IN-16 inhibits the proliferation, migration, and invasion of gastric cancer cells, induces cell cycle arrest and apoptosis, and alters cellular metabolism. This compound is applicable for research in tumors such as gastric cancer.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

CAS Number3077970-44-3
MW448.49
FormulaC25H25FN4O3
SMILESO=C(OCC=1C=NC=CC1)NC2=CC=C(C=C2)CNC(=O)C3=CC(F)=CC=C3N4CCCC4
TargetNAMPT,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information