Nalmefene

SKU: orb2565730

Description

Nalmefene (ORF 11676) is a μ-opioid receptor antagonist and partial κ-opioid agonist. It is utilized in research areas including opioid overdose reversal and alcohol dependence studies, with applications in both in vitro receptor binding assays and in vivo behavioral models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 55096-26-9
• MW: 339.43
• Purity: 99.86%
• Formula: C₂₁H₂₅NO₃
• SMILES: O[C@]12[C@@]34C=5C(O[C@]3(C(=C)CC1)[H])=C(O)C=CC5C[C@]2(N(CC6CC6)CC4)[H]
• Target: TLR,Opioid Receptor,ROS,NO Synthase,p38 MAPK,NF-κB,Apoptosis
• Solubility: DMSO:120 mg/mL (353.53 mM)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AV-104, JF 1, JF1, JF-1, Opioid Receptor, OpioidReceptor, ORF11676, ORF-11676, ORF 11676, TH-104

Compound Identifiers

PubChem CID

5284594