N6-Ethyladenosine

SKU: orb1309363

Description

N6-Ethyladenosine is a potent agonist for human adenosine receptors, exhibiting high affinity for hA1AR and hA3AR with Ki values of 4.9 nM and 4.7 nM, respectively. This small molecule is a valuable research tool for investigating adenosine receptor signaling in cardiovascular, neurological, and inflammatory models, both in vitro and in vivo.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 14357-08-5
• MW: 295.29
• Purity: 99.98%
• Formula: C₁₂H₁₇N₅O₄
• SMILES: CCNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
• Target: Adenosine Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (11.18 mM);DMSO:83.33 mg/mL (282.2 mM)

Bioactivity

• Target IC50:
  A1AR (human):4.9 nM (Ki)|A3AR (human):4.7 nM (ki)
• In Vitro:
  N6-Ethyladenosine exhibits more selectivity at hA1AR and hA3AR over hA2AR with Ki of 8900±770 nM .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

P1 receptor, A2A, A3A, Adenosine Receptor, AdenosineReceptor, inhibit, N6Ethyladenosine, N-6-Ethyladenosine, N6-Ethyladenosine, N6 Ethyladenosine, Inhibitor

Compound Identifiers

PubChem CID

15160100