N3-Ph-NHS ester

SKU: orb1307334

Description

The N3-Ph-NHS ester is a non-cleavable linker used in constructing antibody-drug conjugates (ADCs) for targeted cancer therapy research. Its stable design is applicable in both in vitro biochemical assays and in vivo preclinical studies to develop stable, potent therapeutic agents.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 53053-08-0
• MW: 260.21
• Purity: 99.35% (May vary between batches)
• Formula: C₁₁H₈N₄O₄
• SMILES: [N-]=[N+]=Nc1ccc(cc1)C(=O)ON1C(=O)CCC1=O
• Target: ADC Linker,PROTAC Linker
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.69 mM);DMSO:30 mg/mL (115.29 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Non-cleavable, inhibit, Inhibitor, N3PhNHS ester, N-3-Ph-NHS ester, N3-Ph-NHS ester, N3 Ph NHS ester, Antibody-drug conjugates linkers, ADC Linker, ADC Linkers, ADCLinker

Compound Identifiers

PubChem CID

122153