N3-C4-NHS ester

SKU: orb1307337

Description

The N3-C4-NHS ester is a non-cleavable linker designed for constructing stable antibody-drug conjugates (ADCs). It is widely used in ADC research for both in vitro and in vivo studies to develop targeted cancer therapeutics, facilitating the covalent attachment of cytotoxic payloads to antibodies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 478801-48-8
• MW: 240.22
• Purity: 99.78% (May vary between batches)
• Formula: C₉H₁₂N₄O₄
• SMILES: O(C(CCCCN=[N+]=[N-])=O)N1C(=O)CCC1=O
• Target: ADC Linker,PROTAC Linker
• Solubility: DMSO:Soluble

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Non-cleavable, N3 C4 NHS ester, N3C4NHS ester, N-3-C4-NHS ester, N3-C4-NHS ester, Antibody-drug conjugates linkers, ADC Linker, ADCLinker, ADC Linkers

Compound Identifiers

PubChem CID

11128400