N3-C3-NHS ester

SKU: orb1307338

Description

The N3-C3-NHS ester is a non-cleavable linker used in constructing antibody-drug conjugates (ADCs) for targeted cancer therapy. Its stable design ensures the cytotoxic payload remains attached to the antibody during circulation, making it suitable for both in vitro biochemical studies and in vivo preclinical research models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 943858-70-6
• MW: 226.19
• Purity: 99.92% (May vary between batches)
• Formula: C₈H₁₀N₄O₄
• SMILES: [N-]=[N+]=NCCCC(=O)ON1C(=O)CCC1=O
• Target: ADC Linker,PROTAC Linker
• Solubility: DMSO:100 mg/mL (442.11 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (17.68 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Non-cleavable, N3 C3 NHS ester, N3C3NHS ester, N-3-C3-NHS ester, N3-C3-NHS ester, Inhibitor, Antibody-drug conjugates linkers, ADCLinker, ADC Linkers, ADC Linker

Compound Identifiers

PubChem CID

59248187