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N1,N11-Diethylnorspermine

SKU: orb1689671

Description

N1,N11-Diethylnorspermine (DENSPM) is a polyamine analog that induces cytotoxic effects in glioblastoma multiforme (GBM) cells. It functions by potently activating SSAT and polyamine catabolism, leading to hydrogen peroxide generation, mitochondrial cytochrome c release, and caspase-3 activation. This molecule is a valuable tool for studying polyamine metabolism in cancer research, both in vitro and in vivo.

Research Area

Cell Biology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

CAS Number121749-39-1
MW244.42
FormulaC13H32N4
SMILESC(CNCCCNCC)CNCCCNCC
TargetOthers,mTOR,Caspase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information