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N-Sterol

SKU: orb3137626

Description

N-Sterol is a sterol lipid employed in the formation of lipid nanoparticles (LNP) for delivering mRNA both in vitro and in vivo. N-Sterol LNPs are absorbed by J774A.1 macrophages in a manner dependent on lipid composition, involving clathrin-coated pits, caveolin-mediated endocytosis, micropinocytosis, or phagocytosis at varying frequencies.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number3069417-18-8
MW527.82
FormulaC34H57NO3
SMILESC[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C[C@@H](OC(C=CN(CCOC)C)=O)CC2)[H])[H]
TargetLiposome

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information