N-Stearoylsphingosine

SKU: orb1694298

Description

N-Stearoylsphingosine (Cer(d18:1/18:0)) is a bioactive sphingolipid that activates protein phosphatase 2A (PP2A) by disrupting its interaction with inhibitor 2, resulting in Akt dephosphorylation. This compound is utilized as a research tool in prostate cancer studies, with applications in both in vitro and in vivo experimental models to investigate PP2A-mediated signaling pathways.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2304-81-6
• MW: 565.95
• Purity: 99.89% (May vary between batches)
• Formula: C₃₆H₇₁NO₃
• SMILES: CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)\C=C\CCCCCCCCCCCCC
• Target: Endogenous Metabolite,Phosphatase
• Solubility: DMF:0.15 mg/mL (0.27 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:2.5 mg/mL (4.42 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

d18:1/18:0, Cer(d18:1/18:0), C18 Ceramide, C18 Ceramide (d18:1/18:0), C(18:0)/C(18:1), N-Stearoylsphingosine, PP2A

Compound Identifiers

PubChem CID

5283565