N-Hydroxysulfosuccinimide sodium

SKU: orb1307987

Description

N-Hydroxysulfosuccinimide sodium salt is a water-soluble, non-cleavable linker chemistry essential for constructing stable antibody-drug conjugates (ADCs). It is widely used in both in vitro and in vivo research to develop targeted cancer therapeutics by permanently coupling cytotoxic payloads to antibodies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 106627-54-7
• MW: 217.13
• Purity: 98.73% (May vary between batches)
• Formula: C₄H₄NNaO₆S
• SMILES: [Na+].ON1C(=O)CC(C1=O)S([O-])(=O)=O
• Target: PROTAC Linker,ADC Linker
• Solubility: DMSO:10 mM

Bioactivity

• In Vitro:
  ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ADCLinker, ADC Linkers, ADC Linker, Antibody-drug conjugates linkers, Inhibitor, N-Hydroxysulfosuccinimide, NHydroxysulfosuccinimide sodium, N-Hydroxysulfosuccinimide sodium, Non-cleavable, inhibit, N Hydroxysulfosuccinimide sodium

Compound Identifiers

PubChem CID

3520574