N-Desmethyl-Apalutamide

SKU: orb1309372

Description

N-Desmethyl-Apalutamide is the primary active metabolite of the androgen receptor antagonist Apalutamide. It is used in research to study the pharmacokinetics, metabolism, and anti-proliferative effects of this drug class in prostate cancer models, both in vitro and in vivo.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1332391-11-3
• MW: 463.41
• Purity: 98.60% (May vary between batches)
• Formula: C₂₀H₁₃F₄N₅O₂S
• SMILES: NC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C11CCC1)c1cnc(C#N)c(c1)C(F)(F)F
• Target: Androgen Receptor,Cytochromes P450
• Solubility: DMSO:50 mg/mL (107.9 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CYP2C8, CYP3A4, CYP2B6, CYPs, Cytochrome P450, Androgen Receptor, AndrogenReceptor, Metabolite, N-Desmethyl Apalutamide, NDesmethylApalutamide, N-Desmethyl-Apalutamide, Inhibitor, inhibit, N Desmethyl Apalutamide, pharmacological, plasma-proteins

Compound Identifiers

PubChem CID

86683490