N-Deshydroxyethyl Dasatinib

SKU: orb1987684

Description

N-Deshydroxyethyl Dasatinib is a metabolite of the anticancer drug Dasatinib and a key component in the SNIPER molecule BMS-354825, which targets ABL for degradation. This research compound is utilized in biochemical studies to investigate targeted protein degradation strategies in cancer and immunological research, both in vitro and in vivo.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 910297-51-7
• MW: 443.95
• Purity: 98.42% (May vary between batches)
• Formula: C₂₀H₂₂ClN₇OS
• SMILES: N(C1=CC(=NC(C)=N1)N2CCNCC2)C=3SC(C(NC4=C(C)C=CC=C4Cl)=O)=CN3
• Target: Drug Metabolite,IAP
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.51 mM);DMSO:49.5 mg/mL (111.5 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Drug Metabolite, DrugMetabolite, BCR-ABL, IAP, N-Deshydroxyethyl BMS 354825, N-Deshydroxyethyl BMS354825, N-Deshydroxyethyl BMS-354825, N-Deshydroxyethyl Dasatinib

Compound Identifiers

PubChem CID

11669430