N-Descyclopropanecarbaldehyde Olaparib

SKU: orb1909117

Description

N-Descyclopropanecarbaldehyde Olaparib, an Olaparib analogue, incorporates a DOTA moiety. It acts as a CRBN-based ligand for the formation of novel dual EGFR and PARP PROTAC, DP-C-4. N-Descyclopropanecarbaldehyde Olaparib is suitable for radiolabeling with F-18 or a fluorophore to visualize tumors using positron emission tomography (PET) or optical imaging.

Research Area

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

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Key Properties

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CAS Number	763111-47-3
MW	366.39
Formula	C₂₀H₁₉FN₄O₂
SMILES	Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCNCC1
Target	E3 Ligase Ligand-Linker Conjugate,Others,PARP

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

E3 Ligase Ligand-Linker Conjugate,Others,PARP

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