N-Deacetyl-N-formylcolchicine

SKU: orb3135880

Description

N-Deacetyl-N-formylcolchicine (N-Formyl-N-deacetylcolchicine, Compound 11) is a selective inhibitor targeting the colchicine binding site on tubulin. It exhibits antiproliferative activity against various cancer cell lines, with IC50 values ranging from 32.61 to 100.28 nM. This compound inhibits microtubule polymerization, blocking cell division, inducing apoptosis in cancer cells, and suppressing cellular migration. N-Deacetyl-N-formylcolchicine shows potential for research in lung cancer and other solid tumors.

Research Area

Signal Transduction

Key Properties

• CAS Number: 7411-12-3
• MW: 385.41
• Formula: C₂₁H₂₃NO₆
• SMILES: O(C)C1=C2C=3C([C@@H](NC=O)CCC2=CC(OC)=C1OC)=CC(=O)C(OC)=CC3
• Target: Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Microtubule Associated