N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine

SKU: orb1298237

Description

This novel 2,6-naphthyridine derivative was identified via HTS as a dual inhibitor of protein kinase C and D (PKC/PKD). It serves as a valuable research tool for investigating PKC/PKD signaling pathways in cancer and cardiovascular diseases, with utility in both in vitro enzymatic and cellular assays.

Research Area

Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1071135-06-2
• MW: 388.51
• Purity: 98.35% (May vary between batches)
• Formula: C₂₃H₂₈N₆
• SMILES: C1CCC(CC1)NC1=NC=CC(=C1)C1=CC2=C(C=CN=C2)C(=N1)N1CCNCC1
• Target: Serine/threonin kinase,PKC
• Solubility: DMSO:insoluble

Bioactivity

• Target IC50:
  PKD1:0.6 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NCyclohexyl4[1(1piperazinyl)2,6naphthyridin3yl]2pyridinamine, N Cyclohexyl 4 [1 (1 piperazinyl) 2,6 naphthyridin 3 yl] 2 pyridinamine, PKD, PKC, Serine kinase, threoninkinase, Serinekinase, threonin kinase

Compound Identifiers

PubChem CID

25020250