N-(Amino-PEG5)-N-bis(PEG4-acid)

SKU: orb1989074

Description

This heterobifunctional PEG linker features a central amine and two terminal carboxylic acids, designed for constructing PROTAC molecules. Its flexible, hydrophilic PEG spacers are crucial for optimizing PROTAC efficacy in both cellular and in vivo studies by influencing ternary complex formation and pharmacokinetics.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2093152-86-2
• MW: 776.91
• Formula: C₃₄H₆₈N₂O₁₇
• SMILES: NCCOCCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(O)=O)CCOCCOCCOCCOCCC(O)=O
• Target: PROTAC Linker,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

126480471