N-Acetyl-Calicheamicin

SKU: orb1709070

Description

N-Acetyl-Calicheamicin is a potent antitumor antibiotic used in biochemical research. It is widely studied in vitro for its DNA-cleaving mechanism and in vivo within antibody-drug conjugate (ADC) platforms for targeted cancer therapy.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 108212-76-6
• MW: 1410.38
• Purity: 99.59% (May vary between batches)
• Formula: C₅₇H₇₆IN₃O₂₂S₄
• SMILES: C(\CSSSC)=C/1\C=2[C@@H](O[C@H]3[C@H](O[C@H]4C[C@H](OC)[C@@H](N(C(C)=O)CC)CO4)[C@@H](O)[C@H](NO[C@H]5C[C@H](O)[C@H](SC(=O)C6=C(OC)C(OC)=C(O[C@H]7[C@H](O)[C@H](OC)[C@@H](O)[C@H](C)O7)C(I)=C6C)[C@@H](C)O5)[C@@H](C)O3)C#C/C=C/C#C[C@]1(O)CC(=O)C2NC(OC)=O
• Target: DNA/RNA Synthesis,Antibacterial,ADC Cytotoxin,Antibiotic
• Solubility: DMSO:70.52 mg/mL (50 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, N Acetyl Calicheamicin, NAcetylCalicheamicin, N-Acetyl-Calicheamicin, N-Acetyl-Calicheamicin gamma, N-Acetyl-Calicheamicin r, N-Acetyl-Calicheamicin γ, N-Acetyl-gamma-calicheamicin, N-Acetyl-r-calicheamicin, N-Acetyl-γ-calicheamicin

Compound Identifiers

PubChem CID

131843887