N-acetyl-5-Aminosalicylic Acid

SKU: orb1694382

Description

N-Acetyl-5-Aminosalicylic Acid is the primary acetylated metabolite of the anti-inflammatory drug mesalazine. It is utilized in research to study drug metabolism, pharmacokinetics, and the mechanisms of mesalazine in models of inflammatory bowel disease, both in vitro and in vivo.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 51-59-2
• MW: 195.17
• Formula: C₉H₉NO₄
• SMILES: CC(=O)Nc1ccc(O)c(c1)C(O)=O
• Target: Others
• Solubility: Methanol:8 mg/mL (40.99 mM);DMSO:40 mg/mL (204.95 mM)

Bioactivity

• In Vitro:
  N-acetyl-5-Aminosalicylic Acid is a PP2A inhibitor. N-acetyl-5-Aminosalicylic Acid can be used in the study of ulcerative colitis. The inhibitory effect of flavonoids on the effluents of N-acetyl-5-Aminosalicylic Acid formed in Caco-2 cells.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

N acetyl 5 Aminosalicylic Acid, N-Acetyl mesalazine, Nacetyl5Aminosalicylic Acid, N-acetyl-5-Aminosalicylic Acid, N-acetyl-ASA

Compound Identifiers

PubChem CID

65512