N-(2-Hydroxypropyl)methacrylamide

SKU: orb1309377

Description

This monomer is utilized to synthesize biocompatible copolymers designed for targeted drug delivery. These polymers are researched for the delivery of antileishmanial drugs in models of Visceral Leishmaniasis, with studies conducted in both in vitro and in vivo experimental settings.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 21442-01-3
• MW: 143.18
• Purity: 99.87% (May vary between batches)
• Formula: C₇H₁₃NO₂
• SMILES: CC(O)CNC(=O)C(C)=C
• Target: Others,Parasite
• Solubility: DMSO:3.67 mg/mL (25.63 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (6.98 mM)

Bioactivity

• In Vivo:
  N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates (5 mg/kg) contains lysosomally degradable side chains and shows significant antileishmanial activity (>99% inhibition) in vivo .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

N (2 Hydroxypropyl)methacrylamide, inhibit, N(2Hydroxypropyl)methacrylamide, N-(2-Hydroxypropyl)methacrylamide, Leishmania tropica, leishmaniasis, Inhibitor, copolymers, delivery, antileishmanial, agents, Visceral, synthesize

Compound Identifiers

PubChem CID

38622