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Myrothecine A

SKU: orb2283190

Description

Myrothecine A is a trichothecene mycotoxin with anticancer activity, inhibiting proliferation in A549, MCF-7, HepG2, and SMMC-7721 cells. It induces G1 phase arrest and promotes apoptosis via increased Bax and cleaved caspases, supporting its use in oncology and cell biology research for studying cytotoxic mechanisms.

Research Area

Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

CAS Number910292-40-9
MW546.61
FormulaC29H38O10
SMILESCC(=O)C12CC\C=C/C(=O)OC3CC4OC5C6CC4(O)C3(C)C5(CCC6(C)O)COC(=O)\C=C(\CCO1)C2O |c:6,t:36,TLB:13:18:25.24.23:15,11:20:25.24.23:15,19:18:25.24.23:15,THB:25:16:22.20:13.14,19:18:22.15.14:12.11,17:18:22.15.14:12.11,21:20:25.24.23:15|
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information