Myricetin 3-O-galactoside

SKU: orb1684391

Description

Myricetin 3-O-galactoside is a bioactive flavonoid with potent antioxidant properties, notably inhibiting xanthine oxidase and lipid peroxidation (IC₅₀ = 160 µg/mL). Its primary mechanism involves suppressing inducible nitric oxide synthase (iNOS) synthesis, supporting research applications in studying oxidative stress and inflammation in cellular models.

Research Area

Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 15648-86-9
• MW: 480.38
• Purity: 99.38% (May vary between batches)
• Formula: C₂₁H₂₀O₁₃
• SMILES: OC[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2cc(O)c(O)c(O)c2)[C@H](O)[C@@H](O)[C@H]1O
• Target: Xanthine Oxidase|||NOS

Bioactivity

• Target IC50:
  ACE:20.3 μM
• In Vitro:
  The anti-mutagenesis activity was evaluated by SOS color rendering test and Comet test. The IC50 values of myricetin 3-O-galactoside and myricetin 3-o-rhamnoside for lipid peroxidation were 160 μg /ml and 220 μg /ml, respectively. At the concentration of 100 μg /ml, the two compounds showed the strongest inhibitory effects on xanthine oxidase activity (57% and 59%, respectively). Myricetin 3-0-rhamnoside is a very effective free radical scavenger with an IC50 value of 1.4 MCG/ml. In addition, these two compounds showed inhibitory activity against mutagenesis induced by nifuran, aflatoxins B1 and H2O2.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NOS, Myricetin 3-O-β-D-galactopyranoside, Myricetin 3-O-galactoside, Myricetin 3-O-b-D-galactopyranoside, Myricetin 3-O-beta-D-galactopyranoside, NO Synthase, PARP, iNOS, Xanthine Oxidase, XanthineOxidase

Compound Identifiers

PubChem CID

5491408