MyD88-IN-4

SKU: orb3173791

Description

MyD88-IN-4 is a MyD88 inhibitor. It exerts antiviral effects by upregulating IFN-β and demonstrates anti-inflammatory properties by inhibiting the production of pro-inflammatory cytokines. MyD88-IN-4 prevents the formation of MyD88 homodimers and interferes with its interaction with IRF3/IRF7. In a mouse model infected with VEEV TC-83, MyD88-IN-4 shows efficacy against encephalitic alphavirus infections by reducing viral replication and increasing survival rates. This compound is applicable for research on alphavirus infections, bacterial toxin-related diseases, and sepsis.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 1801552-15-7
• MW: 713.02
• Formula: C₄₄H₆₄N₄O₄
• SMILES: N([C@H](C(=O)N1CCCC1)C(C)C)(C(=O)[C@@H]2CC[C@@H](C(N([C@H](C(=O)N3CCCC3)C(C)C)CCCC4=CC=CC=C4)=O)CC2)CCCC5=CC=CC=C5
• Target: MyD88,IFNAR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

MyD88,IFNAR