MY-1576

SKU: orb2944737

Description

MY-1576 is a potent FAK inhibitor (IC50 = 8 nM) that activates the Hippo pathway to suppress YAP/TAZ activity. It demonstrates robust anti-tumor efficacy in KYSE30 xenograft models and effectively reduces FAK autophosphorylation and YAP/TAZ levels in vivo, supporting its use in cancer research.

Research Area

Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3097026-24-6
• MW: 509.01
• Formula: C₂₅H₂₉ClN₈O₂
• SMILES: CNC(C1=CC=CC=C1NC2=NC(NC3=CC=C(NC(N4CCN(CC)CC4)=O)C=C3)=NC=C2Cl)=O
• Target: YAP,Hippo pathway,FAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

YAP,Hippo pathway,FAK