Multi-target kinase-IN-10

SKU: orb3210648

Description

Multi-target kinase-IN-10 (Compound 6l) is an orally active, brain-penetrant, selective, reversible, and competitive MAO-B inhibitor with an IC50 of 0.0053 μM. It competes with substrates for binding to the active site of MAO-B, chelates Cu2+ ions, inhibits Cu2+-induced ROS production, and decreases the release of NO, TNF-α, and IL-1β. Multi-target kinase-IN-10 shows potential for improving Parkinson's disease.

Key Properties

• CAS Number: 3022330-81-7
• MW: 296.30
• Formula: C₁₇H₁₃FN₂O₂
• SMILES: FC1=CC=C(C=C1)COC=2N=NC(=CC2)C3=CC=CC=C3O
• Target: Monoamine Oxidase,Interleukin,NO Synthase,ROS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Monoamine Oxidase,Interleukin,NO Synthase,ROS