Multi-kinase-IN-7

SKU: orb3173762

Description

Multi-kinase-IN-7 is a multi-kinase inhibitor with IC50 values of 2.19, 2.95, 3.59, and 9.31 μM against EGFR, VEGFR2, TrKA, and CDK2, respectively. It demonstrates moderate to weak activity on FAK, AKT1, GSK3β, and CDK5, with IC50 values of 6.3, 9.2, 11.7, and 23.4 μM, respectively. Multi-kinase-IN-7 exhibits broad-spectrum antiproliferative potential against NCI cancer cell lines and can induce cell cycle arrest, apoptosis (apoptosis), and necrosis. MDA-MB-231 is applicable in breast cancer research.

Research Area

Cardiovascular Research, Cell Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• Target: Trk receptor,CDK,FAK,VEGFR,Akt,GSK-3,EGFR,Bcl-2 Family,Apoptosis,Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Trk receptor,CDK,FAK,VEGFR,Akt,GSK-3,EGFR,Bcl-2 Family,Apoptosis,Caspase