MU262

SKU: orb3173002

Description

MU262 is a structurally novel polycyclic heterocyclic small-molecule compound and a MUS81 inhibitor with an IC50 value of 0.87 μM, which directly inhibits MUS81 catalytic activity through non-interfering DNA binding, inducing genomic instability in tumor cells and specifically inhibiting the HR/BIR repair pathways. MU262 can serve as a chemical biology tool for studying MUS81 function and as a lead compound for developing anticancer therapies that exploit DNA repair defects in cancer cells.

Key Properties

• CAS Number: 1846587-13-0
• MW: 374.38
• Formula: C₂₀H₁₅FN₆O
• SMILES: FC1=CC=C(C=C1)C2=C3N=NC(C4=NC=5C=CC=CC5N4)=C(O)N3N=C2CC
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others