MU1409

SKU: orb2944759

Description

MU1409 is a small molecule inhibitor of MRE11 nuclease (IC50=12.1 µM) that also suppresses FEN1 and EXO1. It disrupts DNA repair pathways and stabilizes stalled replication forks in BRCA2-deficient cells, making it a valuable research tool for studying synthetic lethality and BRCA-mutant cancer models in vitro.

Research Area

Cell Biology

Key Properties

• CAS Number: 2379671-78-8
• MW: 456.312
• Formula: C₂₀H₁₄BrN₃O₃S
• SMILES: C(C=1N=C(NC(/C(=C/C2=CC(Br)=C(O)C(O)=C2)/C#N)=O)SC1)C3=CC=CC=C3
• Target: Endonuclease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146205778