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MTX-531

MTX-531

Catalog Number: orb2564258

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Catalog Numberorb2564258
CategorySmall Molecules
DescriptionMTX-531 is a selective inhibitor of EGFR and PI3K with IC50 of 14.7 nM and 1.1-233 nM (PI3Kα, PI3Kβ...), respectively. It also acts as a weak agonist of PPARγ, with an EC50 of 3.4 μM in 293H cells.
Purity98.00%
MW453.94
CAS Number2791417-66-6
FormulaC22H20ClN5O2S
SMILESN([C@H](C)C1=CC=CC=C1)C=2C3=C(C=CC(=C3)C=4C=C(NS(C)(=O)=O)C(Cl)=NC4)N=CN2
Storage-20°C
NoteFor research use only