mTOR inhibitor 9a

SKU: orb1819210

Description

This compound, a potent mTOR inhibitor, exhibits an IC50 of 80 nM against human LNCaP prostate cancer cell growth in vitro. Its antitumor potential is supported by research into mTOR pathway biology and oncology, suggesting utility in both cellular and preclinical animal studies.

Key Properties

• CAS Number: 1144075-32-0
• MW: 395.48
• Purity: 99.96% (May vary between batches)
• Formula: C₂₀H₂₁N₅O₂S
• SMILES: N(C(NC)=O)C1=CC=C(C2=NC(=C3C(=N2)C=CS3)N4CC5OC(C4)CC5)C=C1
• Target: Others
• Solubility: DMSO:12 mg/mL (30.34 mM)

Bioactivity

• Target IC50:
  PIK3CA:0.423 µM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1methyl3{4[4(8oxa3azabicyclo[3.2.1]oct3yl)thieno[3,2d]pyrimidin2yl]phenyl}urea, mTOR inhibitor 9a

Compound Identifiers

PubChem CID

46227596