MTOB

SKU: orb1304291

Description

MTOB (α-keto-γ-Methylthiobutyric acid) is a small molecule inhibitor of the transcriptional co-repressor CtBP, disrupting its oncogenic functions. It has been shown to inhibit cancer cell proliferation and modulate TCF-4/Wnt signaling pathways in both cellular assays and in vivo mouse models, making it a valuable research tool for studying cancer stemness and tumorigenesis.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 51828-97-8
• MW: 170.16
• Purity: 99.53% (May vary between batches)
• Formula: C₅H₇NaO₃S
• SMILES: [Na+].CSCCC(=O)C([O-])=O
• Target: DNA/RNA Synthesis,Others
• Solubility: DMSO:55 mg/mL (323.23 mM);PBS:100 mg/mL (587.68 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CtBP, 4-methylthio 2-oxobutyric acid, 4-methylthio 2-oxobutyric acid sodium salt, a-keto-r-Methylthiobutyric acid, alpha-keto-gamma-Methylthiobutyric acid, KMBA, MTOB, MTOB salt, MTOB sodium salt, TBI, traumatic brain injury, α-keto-γ-Methylthiobutyric acid, α-keto-γ-Methylthiobutyric acid sodium salt

Compound Identifiers

PubChem CID

23696623