MTH1 degrader-1

SKU: orb2814499

Description

MTH1 degrader-1 is a small molecule inhibitor of MTH1 (aTAG) that functions as a targeting ligand for PROTAC construction. It is utilized in chemical biology research, including the synthesis of PROTAC molecules like aTAG 4531, for studying targeted protein degradation in cellular models.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2412987-06-3
• MW: 459.44
• Formula: C₂₆H₁₉F₂N₃O₃
• SMILES: O=C(O)C=1C=CC(=CC1F)C2=CC=3C(=NC=C(C(=O)NC4CC4)C3NC=5C=CC=CC5)C=C2F
• Target: DNA/RNA Synthesis,Ligands for Target Protein for PROTAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

152172355