MST-312

SKU: orb1303124

Description

MST-312

Research Area

Molecular Biology

Key Properties

• CAS Number: 368449-04-1
• MW: 380.35
• Purity: 99.61%
• Formula: C₂₀H₁₆N₂O₆
• SMILES: Oc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O
• Target: Telomerase
• Solubility: H2O:Insoluble;DMSO:250 mg/mL (657.29 mM);2% DMSO+40% PEG300+5% Tween 80+ 53% Saline:5 mg/mL (13.15 mM)

Bioactivity

• In Vitro:
  In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

gallate, EGCG, epigallocatechin, myeloma, multiple, MST312, MST-312, MST 312, inhibit, Inhibitor, derivative, cancer, tea, Telomerase Inhibitor IX, Telomerase

Compound Identifiers

PubChem CID

10385095