MS9715

SKU: orb2277811

Description

MS9715 is a potent and selective PROTAC degrader of NSD3, constructed from a BI-9321-derived PWWP1 domain binder and a VHL E3 ligase ligand. It serves as a valuable chemical probe for investigating NSD3 biology and its therapeutic potential in cancers, supporting both in vitro and in vivo degradation studies.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• MW: 1028.33
• Formula: C₅₈H₇₄FN₉O₅S
• SMILES: CC1=CC(CNCCCC(NCCCCCCCCC(N[C@@H](C(C)(C)C)C(N2[C@H](C(N[C@@H](C)C3=CC=C(C4=C(C)N=CS4)C=C3)=O)C[C@@H](O)C2)=O)=O)=O)=CC(C)=C1C5=C(C6=CC=NC7=C6C=CC(F)=C7)N(C)C=N5
• Target: Histone Methyltransferase,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510424