MS934

SKU: orb2278171

Description

MS934 is a potent, novel VHL-recruiting degrader of MEK1/2, demonstrating strong anti-proliferative activity with a GI50 of 0.023 µM in HT-29 cells. It is a valuable research tool for investigating multiple cancer types, including melanoma, NSCLC, colorectal cancer, and hepatocellular carcinoma, in both in vitro and in vivo studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2756323-15-4
• MW: 1104.11
• Formula: C₅₂H₆₉F₃IN₇O₆S
• SMILES: C([C@@H](NC(CCCCCCCCCCCNCCCCONC(=O)C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)=O)[C@](C)(C)C)(=O)N3[C@H](C(N[C@@H](C)C4=CC=C(C=C4)C5=C(C)N=CS5)=O)C[C@@H](O)C3
• Target: MEK,Raf,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162504450