MS8511 hydrochloride

SKU: orb2945889

Description

MS8511 hydrochloride is a covalent, irreversible inhibitor selectively targeting G9a and GLP histone methyltransferases (IC50s: 100 nM and 140 nM). It effectively diminishes H3K9me2 levels and demonstrates anti-proliferative effects, supporting its use in epigenetic cancer research both in vitro and in vivo.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 3031788-28-7
• MW: 532.12
• Purity: 99.24% (May vary between batches)
• Formula: C₂₈H₄₂ClN₅O₃
• SMILES: Cl.O=C(C=C)NC=1N=C2C=C(OCCCN3CCCC3)C(OC)=CC2=C(C1)NC4CCN(CC4)C(C)C
• Target: Histone Methyltransferase
• Solubility: Methanol:24 mg/mL (45.1 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MS8511 HCl, MS-8511 HCl, MS-8511 hydrochloride

Compound Identifiers

PubChem CID

171360694