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MS6178

SKU: orb3210431

Description

MS6178 is a CFTR-targeted deubiquitinase chimera (DUBTAC) based on MS5105, which recruits OTUB1 in a concentration and time-dependent manner to stabilize the ΔF508-CFTR mutant protein. This effect is dependent on OTUB1 and does not affect CFTR mRNA levels. MS6178 is applicable for cancer research.

Images & Validation

Key Properties

CAS Number3060520-53-5
MW898.03
FormulaC47H53F2N7O7S
SMILESC(NC=1N=C(C(C)=CC1)C2=CC(C(NCCCCCCC(NCCC=3SC(=CC3)N4C(=O)CN(C(/C=C/CN(C)C)=O)CC4)=O)=O)=CC=C2)(=O)C5(CC5)C=6C=C7C(=CC6)OC(F)(F)O7
TargetDUB,CFTR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information