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MS117

SKU: orb1689367

Description

MS117 is a potent, cell-active, and irreversible covalent inhibitor of PRMT6, exhibiting an IC50 of 18 nM. This first-in-class small molecule is a valuable chemical probe for investigating PRMT6's role in transcriptional regulation, cancer biology, and other epigenetic research areas in both cellular and biochemical assays.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number2702280-86-0
MW298.38
FormulaC17H22N4O
SMILESO=C(C=C)NC1=CC=CC(=C1)C2=CNC=C2CN(C)CCN
TargetOthers,Histone Methyltransferase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • MS117 [orb1818724]

    >98%

    298.38

    C17H22N4O

    100 mg
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Protocol Information