MS102

SKU: orb3174228

Description

MS102 is an orally active inhibitor of ubiquitin-specific peptidase 2 (USP2) with an IC50 of 5.46 μM. It demonstrates effective antiviral activity against ACE2-dependent coronaviruses. MS102 significantly reduces the abundance of the V domain Ig suppressor of T cell activation (VISTA) protein both in vitro and in vivo. It is applicable in SARS-CoV-2 research and can be combined with anti-PD-1 immunotherapies to enhance antitumor immune responses.

Key Properties

• CAS Number: 3058587-77-9
• MW: 596.44
• Formula: C₂₄H₁₇BrF₃N₃O₃S₂
• SMILES: O=C(NC1=NC(=CS1)C=2C=CC(Br)=CC2)C3=CC(=CC=C3NS(=O)(=O)C4=CC=C(C=C4)C)C(F)(F)F
• Target: DUB,SARS-CoV

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DUB,SARS-CoV