MS049 2HCl (1502816-23-0(free base))

SKU: orb1689994

Description

MS049 is a potent and selective small molecule inhibitor of PRMT4 (CARM1) and PRMT6, with IC50 values of 34 nM and 43 nM, respectively. It shows high selectivity over other PRMTs and methyltransferases. This inhibitor is a valuable chemical probe for investigating the roles of these enzymes in cancer, inflammation, and other diseases in both cellular and animal models.

Research Area

Epigenetics & Chromatin

Key Properties

• Target: Histone Methyltransferase
• Molecular Weight: 321.28
• Purity: 99.90% (May vary between batches)
• Formula: C₁₅H₂₆Cl₂N₂O
• SMILES: Cl.Cl.CNCCN1CCC(CC1)OCc2ccccc2

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Histone Methyltransferase, HistoneMethyltransferase, MS049 2HCl (1502816230(free base)), MS-049 2HCl (1502816-23-0(free base)), MS049 2HCl (1502816-23-0(free base)), MS049 2HCl (1502816 23 0(free base)), PRMT4, PRMT6

Compound Identifiers

PubChem CID

129626588