MRT00033659

SKU: orb1706945

Description

MRT00033659 is a pyrazolo-pyridine analogue functioning as a potent, broad-spectrum kinase inhibitor, notably targeting CK1δ (IC50=0.9 µM) and CHK1 (IC50=0.23 µM). Its mechanism induces p53 pathway activation and E2F-1 destabilization, supporting its application in cancer research for in vitro studies of cell cycle regulation and DNA damage response pathways.

Research Area

Cell Biology, Metabolism Research, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1401731-54-1
• MW: 266.3
• Formula: C₁₅H₁₄N₄O
• SMILES: CC(=O)Nc1cccc(c1)-c1cnc2[nH]nc(C)c2c1
• Target: Others,MDM-2/p53,Early 2 Factor (E2F),Casein Kinase,Chk

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

66555775