MRT-68921 hydrochloride

SKU: orb2655792

Description

MRT-68921 hydrochloride (MRT68921) is a potent, relatively specific inhibitor of both ULK1 and ULK2 with IC50 of 2.9 and 1.1 nM, respectively; inhibits a number of kinases by over 80% in a broad panel of 80 protein kinases, including TBK1 and AMPK; reduces phospho-ATG13 and blocks autophagy in cells.

Key Properties

• CAS Number: 2080306-21-2
• MW: 471.038
• Purity: >98% (HPLC)
• Formula: C₂₅H₃₅ClN₆O
• SMILES: CN1CCC2=C(C1)C=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4CCC4)C5CC5.Cl.Cl
• Target: ULK
• Solubility: H2O: 10 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MRT 68921 hydrochloride | MRT68921 hydrochloride

Quick Database Links

Gene Symbol

ULK