MPXV p37 protein-IN-1

SKU: orb3174265

Description

MPXV p37 protein-IN-1 is a potent and orally effective inhibitor of the monkeypox virus (MPXV) p37 protein. It exhibits significant antiviral activity against MPXV, with an EC50 of 12.14 nM, and shows low cytotoxicity (CC50= 304.63 μM). In mice, MPXV p37 protein-IN-1 demonstrates low toxicity and good tolerability. This compound can be utilized for research into anti-monkeypox virus drugs.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 3096845-40-5
• MW: 375.39
• Formula: C₁₈H₁₅F₂N₃O₂S
• SMILES: O=C1[C@@]2([C@]3([C@]4([C@](C4)([C@@]([C@@]2(C(=O)N1NC(NC5=CC(F)=C(F)C=C5)=S)[H])(C=C3)[H])[H])[H])[H])[H]
• Target: Virus Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Virus Protease