MPT0B390

SKU: orb1297771

Description

MPT0B390 is a small molecule HDAC inhibitor that upregulates TIMP3 expression. This dual activity suppresses tumor progression, metastasis, and angiogenesis, as demonstrated in both cellular assays and in vivo cancer models for research applications.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 1817802-18-8
• MW: 375.4
• Purity: 98.23% (May vary between batches)
• Formula: C₁₇H₁₇N₃O₅S
• SMILES: COc1ccc(cc1)S(=O)(=O)N1CCc2cc(\C=C\C(=O)NO)cnc12
• Target: HDAC
• Solubility: DMSO:245 mg/mL (652.64 mM)

Bioactivity

• In Vitro:
  MPT0B390 exhibits antiproliferative activity against human colon cancer cell line HCT116 (GI50 = 0.03 μM).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

colorectal cancer, colon cancer, angiogenesis, Inhibitor, HCT116, HDAC, HDAC inhibitory ability, Histone deacetylases, metastasis, inhibit, MPT0B 390, MPT0B390, MPT0B-390, TIMP3

Compound Identifiers

PubChem CID

118445158