mPGES-1/sEH-IN-1

SKU: orb2945166

Description

Compound 1f (mPGES-1/sEH-IN-1) is a dual-target inhibitor, potently blocking soluble epoxide hydrolase (sEH; IC50 = 5 µM) and microsomal prostaglandin E synthase-1 (mPGES-1; IC50 = 25 µM). This activity supports its investigation in cancer research and inflammation-related studies using in vitro cellular models.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• MW: 387.355
• Formula: C₂₀H₁₆F₃N₃O₂
• SMILES: CC1=C(C=C(N1)C(=O)NC2=CC(=CC(=C2)N)C(F)(F)F)C(=O)C3=CC=CC=C3
• Target: Prostaglandin Receptor,Epoxide Hydrolase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677051