Mouse IFN-alpha / beta R1 Protein

• Catalog Number: orb1087552
• Category: Proteins
• Description: Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
• Reactivity: Mouse
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 47.6 kDa
• Target: IFN-alpha/beta R1
• Source: Mouse IFN-alpha / beta R1, His Tag (orb1087552) is expressed from human 293 cells (HEK293). It contains AA Glu 27 - Thr 429 (Accession # P33896-1).
• Expression System: HEK293
• Biological Activity: Mouse IFN-alpha / beta R1, His Tagimmobilized on CM5 Chip can bind Mouse IFN-alpha 1, His Tag with an affinity constant of 2.96 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).
• Expression Region: Glu 27 - Thr 429
• Endotoxins: 1.0 EU per μg
• NCBI: NP_034638.2
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.6 kDa. The protein migrates as 57-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

Mouse IFN-alpha / beta R1, His Tag (Cat. No. orb1087552) immobilized on CM5 Chip can bind Mouse IFN-alpha 1, His Tag (Cat. No. orb735042) with an affinity constant of 2.96 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).