Motilin (26-47), human, porcine

SKU: orb1296618

Description

This bioactive fragment of motilin (residues 26-47) acts as a potent endogenous agonist for the motilin receptor, exhibiting high affinity (Ki 2.3 nM) and potency (EC50 0.3 nM) in CHO cell assays. It is a valuable tool for studying gastrointestinal motility mechanisms in both in vitro receptor signaling and in vivo physiological models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 52906-92-0
• MW: 2699.07
• Purity: 98.00% (May vary between batches)
• Formula: C₁₂₀H₁₈₈N₃₄O₃₅S
• SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](C(C)C)NC(=O)[C@H](CC4=CC=CC=C4)N
• Target: Motilin Receptor
• Solubility: DMSO:10 mM

Bioactivity

• Target IC50:
  Motilin receptor (Chinese hamster ovary cells):0.3 nM (EC50)|Motilin receptor (Chinese hamster ovary cells):2.3 nM (Ki)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Motilin (26 47), human, porcine, Motilin (2647), human, porcine, Motilin (26-47), human, porcine, Motilin , human, porcine, Motilin Receptor, MotilinReceptor, inhibit, MLNR, Inhibitor

Compound Identifiers

PubChem CID

16136567