Momordin Ic

SKU: orb1304227

Description

Momordin Ic exhibits potential anticancer activity by triggering apoptosis via oxidative stress and mitochondrial dysfunction, mediated through MAPK/PI3K-regulated iNOS and HO-1 pathways. It also promotes gastrointestinal motility by stimulating 5-HT synthesis and subsequent prostaglandin production via 5-HT2 receptors, as shown in cellular and animal studies.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 96990-18-0
• MW: 764.94
• Purity: 99.69% (May vary between batches)
• Formula: C₄₁H₆₄O₁₃
• SMILES: C[C@]12[C@@]3(C)C([C@]4([C@@](C(O)=O)(CC3)CCC(C)(C)C4)[H])=CC[C@@]1([C@]5(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]6[C@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O)CO7)[C@H](O)[C@@H](C(O)=O)O6)CC5)[H])[H]
• Target: Autophagy,c-Myc,MAPK,Apoptosis,PI3K
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.54 mM);DMSO:125 mg/mL (163.41 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

dysfunction, Apoptosis, MAPK, Inhibitor, Fructus, Kochiae, inhibit, Momordin 1c, Momordin Ic, mitochondrial, PI3K

Compound Identifiers

PubChem CID

14162549