MOMA-341

SKU: orb3134913

Description

MOMA-341 is a selective, ATP-competitive WRN allosteric inhibitor that binds to the cysteine 727 site of WRN. It induces DNA damage, cell death, and tumor regression in dMMR/MSI-H mouse models and can be used to study advanced and metastatic solid tumors.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 3078276-74-8
• MW: 570.54
• Formula: C₂₈H₂₆F₄N₆O₃
• SMILES: C(=O)(N1[C@@]2(C3=C(N(N=C3CCN(C(C=C)=O)C2)C4=C(O)C=C(C=C4)C5CC5)CC1)[H])C=6C(N)=C(F)C(C(F)(F)F)=NC6
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA/RNA Synthesis