Mogroside IIA1

SKU: orb1297279

Description

Mogroside IIA1 is a natural, high-intensity sweetener derived from Siraitia grosvenorii fruit. Research indicates it exhibits antioxidant, antidiabetic, and anticancer properties, making it a compound of interest for metabolic and oncology studies in both in vitro and in vivo models.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 88901-44-4
• MW: 801.01
• Purity: 99.60% (May vary between batches)
• Formula: C₄₂H₇₂O₁₄
• SMILES: [H][C@@]1(CC[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(CC[C@H](O)C4(C)C)[C@]3(C)[C@H](O)C[C@]12C)[C@H](C)CC[C@@H](O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)C(C)(C)O
• Target: NO Synthase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.12 mM);DMSO:95 mg/mL (118.6 mM)

Bioactivity

• In Vitro:
  Mogroside II-A1 exhibits inhibitory effects with IC50 values of 346-400 mol ratio/32 pmol TPA. Mogroside II-A1 showed weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, NOSynthase, Mogroside IIA 1, Mogroside IIA1, Mogroside II-A1, Mogroside IIA-1, NO Synthase

Compound Identifiers

PubChem CID

102086511